The data connection could not be established: EHOSTUNREACH - No route to host

Did you try IP address, use ftp and not sftp to test. Did you try with active mode mode to test?. It does say no route to host. Did you make any changes to the Virtualmin system manually, permission changes or moving directories? Do you have both ipv4 and ipv6 enabled, disable ipv6 to test. Is there another firewall between your server and outside? Sometimes with VPS’s, there is a central firewall in place in addition to local. Can you connect to ftp using from command line/shell.

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