Roundcube SMTP Failure to Sendmail - Outbound Mail Problems

Virtualmin uses Postfix for the MTA not Sendmail. Dovecot is used to for IMAP and POP3 connection to client. Dovecot don’t handle the inbound mail Postfix does.
Using sendmail will break the default virtualmin setup I would think.

I think Roundcube would send via Postfix and you configure postfix to handle the connection to smtp2go

calport may help you