Can not Backup domain or add auto reply to mail alias! Help!

Hey Guys,
I’ve been struggling for a while now trying to figure out this issue and was hoping someone could be so kind as to give me points or tip as to what the problem is.

My Setup:
Ubuntu 14.04.2,
Virtualmin 4.18.gpl,

Everything was working fine. I got an initial backup saved without any issues, but now whenever I try to update the domain again I get the following error:

Failed to open /home/ : Permission denied at /usr/share/webmin/ line 1397, line 1.

On top of that I tried to make a new mail alias and setup an autoreply, and I also get a similar error as follows:

Failed to save alias : Failed to open /home/ : Permission denied

Can anyone please help me with some Ideas as to what the problems are? I really need to get this fixed and get things backing up properly. Any help would be greatly appreciated. Thanks!